Anwar, a former deputy premier who was sacked and jailed on separate sex and corruption counts a decade ago, said Malaysian justice had deteriorated under Prime Minister Najib Abdul Razak, who came to power a year ago.
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Anwar said he would not be cowed by the fact he could again end up behind bars if convicted of the charges that carry a penalty of 20 years imprisonment.
"I am committed to political and economic reforms. There is no turning back," he said.
"Of course I am a political threat. They have been trying for 12 years to kill my political career. I leave it to my supporters and Allah to believe in me."
Severely disadvantaged position
Anwar, a 62-year-old father of six, is accused of having illicit sexual relations with a young man who worked in his office. Sodomy remains a crime in Malaysia, a conservative Muslim-majority nation.
The trial opened briefly in February with explicit evidence from his accuser, 24-year-old Mohamad Saiful Bukhari Azlan, but has been suspended since then as the defence pursued a number of unsuccessful legal manoeuvres.
They were knocked back in attempts to have the presiding judge disqualified, complaining he had refused to rein in biased media coverage, and also failed to win access to key prosecution evidence such as video footage and medical tests.
Anwar last week lost his final bid to strike out the sodomy charges, as the Federal Court rejected an appeal and paved the way for his trial to resume at the High Court on Monday.
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"Anwar is put in a very severely disadvantaged position. The defence faces an uphill task as vital documents in relation to Anwar's defence have not been given to us by the prosecution," he said.
"We intend to grill Saiful'
Human Rights Watch has urged Malaysia to drop the charges against Anwar, condemning the case as a "charade of justice" and saying his lawyers had been blocked from preparing a thorough defence.
Sankara said the defence team would cross-examine Mohamad Saiful when the hearing opens Monday.
"We intend to grill this witness," Nair said. "The court has set four days for this hearing." Hearing dates have been set until August but Sankara said he did not know when the trial would end.
Anwar's earlier sexual misconduct conviction was quashed in 2004 and he was released from jail. After a period of recuperation he reinvented himself as the leader of an opposition alliance.
Against all expectations, it made huge strides in 2008 elections, depriving the ruling coalition of its crucial two-thirds majority and redrawing Malaysia's political landscape.
After suffering its worst polls results in half a century, the shell-shocked Barisan Nasional coalition ousted the serving prime minister and drafted in Najib, who has unveiled reforms aimed at winning back support. - AFP